Projects Sanctioned / Undertaken

Principal Investigator: Prof. Ramesh Chandra (unless stated otherwise)

Design, development and evaluation of inhalable self-assembled nanomicelles of 9-amino-noscapine customized for the treatment of non-small cell lung cancer

Funded by: University of Delhi, Institution of Eminence | Amount: INR 3,00,000 | Duration: 2021-2022

Regulation of RUNX3 through post–translational modifications under the influence of hypoxia in Non-Small Cell Lung Carcinoma

Funded by: University of Delhi, Institution of Eminence | Amount: INR 2,50,000 | Duration: 2020-2021

Biological activity of Pyrazinoindoles and Pyrazinopyrroles in Chlamydia and eukaryotic parasites

Funded by: DST-DAAD | Amount: INR 49 lacs | Duration: 2020-2023

Electrochemical ultra-sensing platform integrated with biomarker coated on graphene detecting neonatal sepsis

Funded by: DBT, Govt. of India | Amount: INR 60 lacs | Duration: 2020-2023

Design and optimization of bio-compatible optical nanostructures for biomedical applications

Funded by: DST SERB (Indo–Russia Joint Project) | Amount: INR 40 lacs | Duration: 2019-2022

Design of Novel Fluorinating Reagent: Application in the synthesis of fluoro organic molecules

Funded by: DRDO under ARMREB | Amount: INR 40 lacs | Duration: 2018-2021

Synthesis and Characterization of Eco-friendly Gold supported LDH catalyst; application in synthesis of organic compounds

Funded by: SERB, DST | Amount: INR 49,61,440 | Duration: 2016-2019

Synthesis and Biological Evaluation of a Novel Class of Anti-tumor drugs based upon the natural alkaloid

Funded by: CSIR | Amount: INR 29,76,540

Design, synthesis and biological screening of chiral pyrazinoindoles and pyrazinopyrroles as potential antibacterial agent

Funded by: SERB, DST | Amount: INR 43,26,000 | Duration: 2016-2020

Development of Tubulin binding Novel Noscapine Derivatives and their nanoparticles for the potential treatment of cancer and drug-resistant cancer

Funded by: University of Delhi R&D scheme | Amount: INR 3,00,000 | Duration: 2015-2016

Nanomedicine nanotechnologie cancer research initiative (International Nanotechnology Collaboration)

Funded by: Quebec MDEIE | Amount: CAD 69,000 | Duration: 2007-2009

Evaluation of a novel tubulin-binding noscapinoid, 9-bromo-noscapine for the management of hormone responsive and refractory breast cancers

Funded by: ICMR | Amount: INR 10,50,000 | Year: 2007

Treatment of hormone and drug sensitive and refractory human breast tumors by augmentation of specific apoptosis by 9-Br-Noscapine and its novel analogs

Funded by: DST | Amount: INR 8,70,000 | Year: 2007 | Co-PI: Prof. Harish Joshi, USA

Commercial production of Bijasal (Pterocarpus marsupium Roxb.)

Funded by: ICMR | Amount: INR 4,11,768 | Year: 2007 | Co-PI: Dr. S. C. Gupta

UGC Assistance to ACBR under SAP I for Drug Discovery & Development

Funded by: UGC | Amount: INR 39,00,000 | Duration: 2007-2012 | Coordinator: Prof. Ramesh Chandra; Co-Coordinator: Dr. Vibha Tandon

Human Resource Development for Biomedical Research (Catch Them Young)

Funded by: CSIR | Amount: INR 7,00,000 per annum | Duration: 2000-2009 | Co-PI: Dr. Y. Singh

Biochemical investigations on antidiabetic effect of Brassica nigra

Funded by: ICMR | Amount: INR 12,00,000 | Year: 2006

Drug Discovery and Development in Biomedical Sciences (Innovative Program)

Funded by: UGC | Amount: INR 39,75,000 | Year: 2005 | Coordinator: Prof. Ramesh Chandra

Molecular mechanism of acetoxy drug: Protein trans-acetylase catalyzed activation of smooth muscle nitric oxide synthase by polyphenolic peracetates

Funded by: DRDO | Amount: INR 9,57,500 | Year: 2005 | Co-PI: Prof. H.G. Raj

A search for some new anti-tumor drugs based upon the natural alkaloid — Noscapine

Funded by: DST | Amount: INR 68,40,000 | Year: 2005

Identification and characterization of antidiabetic compounds from Annona squamosa and Ocimum sanctum

Funded by: ICMR | Amount: INR 5,28,318 | Year: 2005 | Co-PI: Dr. Vibha Tandon

Teaching & Research in Interdisciplinary and Emerging Area

Funded by: UGC | Amount: INR 39,75,000 | Year: 2005

Establishment of High-Resolution NMR Central Facility for Biomedical Research

Funded by: DST | Amount: INR 95,00,000 | Year: 2004 | Co-PI: Dr. Vibha Tandon

Establishment of Liquid Chromatograph - Mass Spectrometer (LC-MS-MS)

Funded by: DST | Amount: INR 75,00,000 | Year: 2003

Design and synthesis of mimic of the dihydropyridine calcium channel modulator and synthesis of piperidine derivatives such as azasugars

Funded by: ICMR | Year: 2003

Role of metalloporphyrins in therapeutics of cardiovascular complications during hypoxic stress

Funded by: ICMR | Amount: INR 8,18,200 | Year: 2003

In vitro propagation of Bijaswal (Pterocarpus marsupium Roxb.): A Medicinal Leguminous Tree

Funded by: DST | Amount: INR 16,13,760 | Year: 2003 | Co-PI: Dr. S. C. Gupta

The Adaptive Medicine and its Relevance

Funded by: DST | Amount: INR 5,13,000 | Year: 2003 | Co-PI: Dr. S. K. Srivastava

Design and synthesis of mimic of the dihydropyridine calcium channel modulator and synthesis of piperidine derivatives such as azasugars

Funded by: ICMR | Amount: INR 7,80,000 | Year: 2003 | Co-PI: Dr. Manisha Tiwari

Computer facility for induction of computer paper at PG level

Funded by: UGC | Amount: INR 2,40,000 | Year: 2002

Synthesis of Oxandrolone

Funded by: HIKMA, Jordan | Amount: USD 30,000 | Year: 2001 | Co-PI: Dr. Vibha Tandon

Standardisation of optimization of morphine and other opium alkaloids by HPLC as stipulated in British Pharmacopoeia

Funded by: CRCL | Amount: INR 7,72,000 | Duration: 1998-2001 | Co-PI: Dr. Pratibha M. Luthra

Human Resource Development for Biomedical Research: CSIR - University Interaction Model

Funded by: CSIR | Amount: INR 13,35,000 | Year: 2000

Effect of active principles of Withania somnifera, Curculigo orchioides, Asparagus racemosus on anti-stress activity in animal models

Funded by: DRDO, Ministry of Defence | Amount: INR 8,08,400 | Year: 1999 | Co-PI: Dr. Manisha Tiwari

Techniques in Recombinant DNA Technology

Funded by: DBT, Government of India | Amount: INR 3,80,000 | Year: 1999

Development of Structure–Activity Relationship of Noscapine - A Potential Antineoplastic Agent

Funded by: UNESCO | Amount: USD 15,000 | Year: 1998

Development of New Synthetic Chemical Methods

Funded by: Polaroid Corporation, USA | Amount: USD 3,50,000 plus equipment and supplies worth ~ USD 5,50,000 | Year: 1996

RGD containing Peptides: Development of Anticancer Agents

Funded by: UGC Career Award | Amount: INR 2,50,000 per annum | Year: 1995

A4 Amyloid Related Proteins from Sperm: Structure, Function and Genetics

Funded by: Rockefeller Foundation (with Population Council, Rockefeller University) | Year: 1992

Synthesis of Organometallic Compounds

Funded by: DRDO | Amount: INR 16,00,000 | Duration: 1990-1992

Biochemical Properties of Metalloporphyrins: Interaction with Apomyoglobin, Heme Binding Proteins and DNA

Funded by: CSIR | Amount: INR 6,50,000 (approx) | Year: 1989

Role of Metals in Biological Systems in vitro and in vivo studies

Funded by: UGC | Year: 1988

Synthesis and Characterisation of Transition Metal Complexes of Macrocyclic ligands with biological relevance

Funded by: UGC | Year: 1987